I-Hyaluronic Acid (HA) iyi-molecule yemilingo esetshenziswa kabanzi emikhakheni yeubuhlekanye nemithi.Ukutholwa kwayo kanye nenqubo yentuthuko ithwala imizamo engapheli kanye nokuqanjwa kabusha kwezobuchwepheshe kososayensi.Lesi sihloko sizocubungula ngemvelaphi, imvelaphi yomlando kanye nokuthuthuka kwei-hyaluronic acidekhulwini lama-20, kwembula uhambo olungavamile lwale molecule.

Okutholwe ngumthombo:

Ukutholwa kwasekuqaleni kwakungo-1934, lapho uKarl Meyer, udokotela wamehlo e-Columbia University, kanye nomsizi wakhe uJohn Palmer behlukanisa i-polysaccharide yamangqamuzana amaningi equkethe i-uronic acid noshukela we-amino emzimbeni wamehlo ezinkomo.Lokhu kutholwa kuphawula ukungena okusemthethweni kwei-hyaluronic acidkososayensi'ama-horizons.Njengoba ingxenye equkethe i-uronic acid ikhishwa emzimbeni we-vitreous, le nto ibizwa ngegamaI-hyaluronic acid, eyaziwa nangokuthii-hyaluronic acid.Khona-ke phakathi nesikhathi esifushane kusukela ngo-1948 kuya ku-1951, osokhemisi abaningana baqala ukutadisha isakhiwo se-hyaluronic acid.

Inkathi entsha yezindlela zokukhipha:

Ngawo-1960, ngokuthuthuka kwesayensi nobuchwepheshe, abacwaningi baqala ukusebenzisa izindlela zokukhipha izicubu ukuze bakhiqize i-hyaluronic acid.Le nqubo ihilela ukukhipha i-hyaluronic acid ezicutshini zezilwane, kodwa yayibiza futhi ayizange ithole ukunakwa okuningi nokusetshenziswa ngaleso sikhathi.Nokho, ukuthuthukiswa kwale ndlela kuye kwakhuthaza ucwaningo olwengeziwe nge-hyaluronic acid emkhakheni wezokwelapha kanye nesayensi yezinto eziphilayo, kwabeka isisekelo sokusetshenziswa kwayo okubanzi esikhathini esizayo.

Ukuqamba izindlela ezintsha zokuvutshelwa:

Ukuqamba okusha kwangempela kwenzeka ngeminyaka yawo-1980, lapho iShiseido yaseJapan iqala ukusebenzisa ukuvutshelwa ukukhiqiza i-hyaluronic acid.Le ndlela yokukhiqiza entsha ayigcini nje ngokuthuthukisa ubumsulwa bei-hyaluronic acid, kodwa futhi inyusa ngokuphawulekayo isivuno sayo, iyenze ibe i-biomaterial ethandwayo.Ukwethulwa kwezindlela zokuvutshelwa kuye kwanweba nakakhulu izinkambu zokusetshenziswa kwe-hyaluronic acid, kuhlanganiseubuhle, imithi kanye nezinhlelo zokulethwa kwezidakamizwa.

Inkathi yegolide yobuhle nemithi:

Njengoba ubuchwepheshe bokukhiqiza i-hyaluronic acid buqhubeka buthuthuka, ekhulwini lama-21, kancane kancane iye yaba inkanyezi.isithakoemkhakheni wobuhle nemithi.Kwezimonyo, i-hyaluronic acid isetshenziswa kakhulu njengesigcwalisi ukuze bushelelezi imibimbi futhi ithuthukiseukunwebeka kwesikhumba.Kwezokwelapha, i-hyaluronic acid isetshenziswa ezindaweni ezifana nesifo samathambo, ukuhlinzwa kwamehlo, nokuphola kwesilonda, okubonisa imiphumela emihle kakhulu yomtholampilo.

Isiphetho:

Uhambo olungokomlando lwe-hyaluronic acid luyamangalisa, kusukela ekutholakaleni kwayo kokuqala kuya ekuthuthukisweni kwezindlela zokuyikhipha kuya ekwethulweni kwezindlela zokuvutshelwa, i-hyaluronic acid iyaqhubeka nokuguquguquka ukuze inikeze izixazululo ezingcono kakhulu kumuntu.yezimonyokanye nezidingo zezokwelapha.Le molecule emangalisayo izoqhubeka idlala indima ebalulekile ocwaningweni lwesayensi kanye nokusebenza kwezokwelapha, ibeka isisekelo esiqinile sokusungula izinto ezintsha nentuthuko yesikhathi esizayo.